WELCOME TO SYSKID: THE FUTURE OF RENAL RESEARCH

SysKid, a large-scale integrating European research project, aims at deepening our understanding of chronic kidney disease. The project paves the way for progress in prevention, new diagnostic strategies and treatment options for declining kidney function, which affects millions of patients suffering from diabetes and hypertension.

FEATURING SYSKID: THE LATEST PAPERS

Follow our featured SysKid publications and 6 questions to the authors about their work:


A Gene Variant in CERS2 Is Associated with Rate of Increase in Albuminuria in Patients with Diabetes from ONTARGET and TRANSCEND

Shiffman D, Pare G, Oberbauer R, Louie JZ, Rowland CM, Devlin JJ, Mann JF, McQueen MJ.

PLoS One. 2014 9(9):e106631

Q&A

1.    What do you like most regarding your findings?

We provided evidence supporting the association of genetic variant in the CERS2 gene with accelerated worsening of albuminuria in diabetic patients drawn from two large randomized clinical trials.

» read more


Analysis of risk factors associated with renal function trajectory over time: a comparison of different statistical approaches

Leffondre K, Boucquemont J, Tripepi G, Stel VS, Heinze G, Dunkler D.

Nephrol Dial Transplant. 2014 Oct 17 [Epub ahead of print]

Q&A

1.    What do you like most regarding your findings?

The paper provides a simple introduction and comparison of the three commonly used statistical methods to analyse the trajectory of renal function over time, and its determinants. Using hypothetical data on 200 CKD patients with 1 to 8 renal function measurements, it illustrates the advantages of the linear mixed model, in particular when patients drop out of the study because of renal replacement therapy.

» read more

MORE TO KNOW

» read our newsletter

» SysKid featured at Fit for Health (youtube)

» webcast: SME success story in FP7, SYSKID

» demo video: watch the SysKid molecular data integration concept

» flyer: download our information folder

MEET US

Stay in touch with the scientists of the SysKid team and find all upcoming events where you can meet members of the SysKid consortium, or relevant meetings in the field of nephrology or systems biology.

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